Multiple Cranial Nerves Palsy In Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma is tumor arising from the epithelium of the nasopharynx. Nasopharyngeal carcinoma may implicate several cranial nerves in succession by invading the base of the skull (mainly the fifth and sixth). Incidence of NPC is usually in late childhood and people aged 50-60 years. This is thought to be due to the Ebstein-Barr virus (EB). Until now the main modality of treatment for nasopharyngeal carcinoma is radiotherapy. This is a case report of male, 60 years, admitted to RSUP. H. Adam Malik Medan with major complain is headache. From neurologic examination we found hyposmia sinistra, diplopia, facialis hemihipestesia sinistra and disfonia. From Head CT-scan shows there is no intracranial SOL and other cerebral abnormalities. Sphenoidalis and ethmoidalis sinusitis dextra/sinistra. Destruction of base skulls ec NPC? Nasopharyngeal biopsy shows non keratinizing squamous cell carcinoma. The patient diagnosed as nasopharyngeal carcinoma.
Keywords: nasopharyngeal carcinoma, ebstein-barr virus