Association Between Epilepsy And Insomnia Symptom
Eva Rahmi Halim, Cut Aria Arina, Yuneldi Anwar
Purpose: The purpose of this study was to confirm hypothesis stated that there were association between epilepsy and insomnia symptom, association between anti epileptic drugs status (mono- therapy and poly-therapy) and insomnia, and association between anti epileptic drugs and insomnia degree.
Methods: This cross sectional study observed 56 epilepsy patients, completed the following questioner Insomnia Severity Index at outpatient clinic for epilepsy in Adam Malik General Hospital. Patients with depression, anxiety and chronic diseases were excluded from this study. All of data were analyzed by chi-square test.
Results: Subjects consists of 27 (48,2%) female and 29 (51,8%) male, with mean age 30,95 years. More than half of the patients (51,8%) experienced insomnia: 16% with mild insomnia and 37,5% with moderate insomnia. There were 26,8% of patients with poly-therapy anti epileptic drugs and insomnia, and 25% of patients with mono-therapy anti epileptic drugs and insomnia. There was no significant association between antiepileptic drugs and insomnia (p= 0,09). Patients who received poly-therapy anti epileptic drugs with mild insomnia was 5,2% and moderate insomnia was 23%, but patients who received mono-therapy anti epileptic drugs with mild insomnia was 10% and moderate insomnia was 14%. There was significant association between antiepileptic drugs status and insomnia degree (p=0,04)
Conclusion: There was a significant association between anti epileptic drugs status and insomnia degree. Further prospective study with larger subjects is needed to confirm this study.
Keywords: epilepsy, insomnia, antiepileptic drug, seizure.